I used once or twice. it made my condition worst. I have colon cancer but I do not know if it is the mode that Vit C is effective on it or not.
About drugs that need refrigeration some one can sell drugs by sending them using iceboxes. Customs keep drugs in refrigerator if it is has mentioned on the package (airplane cargo is cold itself)
I had ordered when weather was became relatively cold (although I told them about icebox but they said it is not needed)